
1) Fuel: combustible dust
2) Oxygen: oxidizer
3) Heat: ignition source
Also:
4) Confinement of a dust cloud
5) Sufficient dispersion of dust particles in quantity and concentration

If one of the elements of the explosion pentagon is missing, a catastrophic explosion cannot occur. Without sufficient heat and oxygen, a fire cannot begin. Without fuel, a fire will stop.
To stop a combustion reaction, one of the three elements has to be removed:
- Suppression of fuel: by closing of the valve fueling the combustion, creating sufficient distance between fire and flame, exhausting hot smoke, etc.
- Suppression of oxygen (choking): use of a carbon dioxide fire-extinguisher, blanket, or spraying sufficient water on a solid combustible
- Suppression of heat (cooling down): by spraying water into a mixture of air and combustible particles, net absorbing the heat, removal of hot smoke

Businesses should identify the following to assess their potential for dust explosions:
- Fine materials that can become airborne and combustible;
- Processes which use, consume, or produce combustible dusts;
- Areas where combustible dusts may accumulate;
- The ways in which dust may become airborne;
- Ignition sources in those areas.
Employers with hazardous chemicals (including combustible dusts) in their workplaces are required to comply with 29 CFR 1910.1200, the Hazard Communication standard. This includes having labels on containers of hazardous chemicals, using material safety data sheets, and providing employee training.